Juvenile Laryngeal Paralysis & Polyneuropathy (JLPP)


JLPP in Rottweilers – FAQ’s

Recently we became aware of an inherited disease in Rottweilers called JLPP (Juvenile Laryngeal Paralysis & Polyneuropathy). As soon as we became aware of this disease many Rottweiler breeders started getting their breeding dogs tested.

How is it inherited?

JLPP is recessive which means that both parents have to be carriers of the JLPP gene in order to produce an affected puppy. If at least one parent is clear then the breeding will not produce an affected puppy. If one parent is a carrier then the breeding will produce both carrier and clear puppies (but no affected). If both parents are clear then the breeding will produce only clear puppies.

Why is it important to test breeding dogs?

It is important to test for this disease as it is always fatal to affected puppies. There is no cure. Symptoms can start to manifest at 12 weeks of age, but, may take longer. Most affected puppies die before 1 year of age. This means that the breeder cannot tell without a DNA test if a puppy is affected before it leaves for its new home at 8 weeks old.

What can I do?

Before buying a Rottweiler puppy make sure at least one of the parents has been tested JLPP clear. For most people (those not looking to breed) it does not matter if one of the parents is a carrier as long as the other is clear.

Do I need to test?

For most the answer is no. Only breeding dogs need to be tested.

If you have any questions about this disease feel free to ask.

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JLPP – Juvenile Laryngeal Paralysis and Polyneuropathy

Understanding JLPP – THE FACTS

There are some breeders of Rottweilers (some registered with ANKC and some not) who will try to tell people looking to buy one of their puppies that Juvenile Laryngeal Paralysis and Polyneuropathy (JLPP) is not a common problem in our breed. We are not hearing of NRC(a) breeders behaving this way, but regardless of this buyers need to be aware of what JLPP is and what to ask the breeder.

We are hearing of breeders who are saying things such as…

“JLPP is no more prevalent in our breed than any other breed.”

FALSE – JLPP only exists in the Rottweiler, Russian Black Terrier and Leonberger.

”Breeders would know if their dogs were JLPP Carriers because they would have seen signs”

FALSE – JLPP Carrier dogs do not exhibit any signs of illness at all. They are a perfectly healthy dog and live a perfectly normal life. It is only when two of these Carrier dogs are mated together that affected puppies can/will be born in a litter.

“Breeders would know if their breeding dogs were Carriers because they have bred
with them previously and all of the puppies were fine”

FALSE – Some breeders do not keep in touch with their puppy people and would not know if they started exhibiting signs of JLPP a month or more after the puppy left. Also given the mode of inheritance of JLPP and the fact that some unborn puppies can die in utero, it is possible that all of the litter ended up being JLPP Clear or Carrier and therefore healthy.

“Educating the public on such diseases in breeds like JLPP is scare mongering”

FALSE – JLPP is real, it exists. We are finding more and more JLPP Carrier dogs becoming apparent within Australia almost every day, as well as around the world. This is a good thing because ethical breeders will use this information to ensure their breeding practises are eliminating any risk at all of producing affected off spring.

“Vets and specialists around Australia say that JLPP is not a problem
in the Rottweiler because it is so rare”

FALSE – Most vets and vet specialists around Australia are still not aware of JLPP. Breeders of Rottweilers are taking this opportunity to educate their vets by way of passing on information to them and encouraging them to find out about this disease.

We cannot express more strongly the importance of asking the breeder you are making inquiries with what the JLPP status of both parents of your puppy is. Insist on seeing the certificates that show this status. Ensure your puppies parents are either both JLPP Clear or only one of them is a JLPP Carrier.

Do not be afraid or embarrassed to walk away from a breeder who will not provide you with the information you are asking to see. There will be another breeder with a lovely puppy who will be forthcoming with JLPP certificates plus all the required health certificates and clearances you are being advised to ask to see.

Original taken from the group “Rottweiler Puppies from NRCA ANKC Registered Breeders” and written by Meg Lewis.

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JLPP FAQ’s for Rottweiler Breeders

Whilst it is not yet compulsory for Rottweiler breeders in Australia to test their breeding dogs for JLPP, it is envisaged that at least at NRCA level it will eventually become compulsory. It is also envisaged that, as with HD/ED results the dog’s microchip number will need to be positively identified when taking DNA samples for testing. Therefore I highly recommend that rather than taking the swab yourself you take your dog/dogs to a vet for the samples to be taken and microchip number to be verified. This way there can be no question of validity, and also ensures your dog’s results will be on the National database.

WHERE CAN I GET MY JLPP TESTS DONE ?
Australia currently do not do the tests, labs in other countries currently testing:

UNITED KINGDOM:
http://www.laboklin.co.uk/laboklin/showGeneticTest.jsp

Members of the ANKC who enclose a copy / scan of their membership will discount the set price down to £44.00 per JLPP test (down from £48.00). They are also able to test semen samples if an AI has taken place (from a used vial with some semen residue). It is not guaranteed but some results have already been achieved with this, if successful the charge will be an extra £25. Laboklin UK has agreed to a "special" discount for those breeders who wish to test litters. For 3+ puppies the test will be 42 pounds. Updates coming soon for procedure on how to test puppies.

Note: this lab accepts other swab kits other than just theirs, so you do not need to wait for theirs to be sent to you – just get your vet to use the swab kits they currently have.

USA:
OFA website for JLPP testing $65US about $87Aust.
http://www.ofa.org/dnatesting/lpp.html

Note: OFA only accept their swab kits, so there is a wait for these to arrive from the US, some 2-4 weeks at the present time.

EUROPE:
http://www.laboklin.de/index.php

OR

https://shop.labogen.com/

Once you get your results back from the laboratory, to add your results to the Australian NRCA Database:
email to nrca.br@gmail.com

OR

Post to: The NRCA Breed Recorder, PO Box 1102 Grovedale DC VIC Australia 3216

JLPP Australia Facebook page: https://www.facebook.com/groups/JLPPinRottweilers/

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